发明名称 NOVEL ANTI-HUMAN CTGF ANTIBODY
摘要 [Problem] To provide: an anti-human CTGF antibody having a superior binding activity and/or a superior neutralization activity compared with those of conventional anti-human CTGF antibodies; and a means for preventing or treating various diseases in which human CTGF is involved in the formation of clinical conditions thereof, including renal diseases such as chronic kidney disease and diabetic nephropathy, using the above-mentioned anti-human CTGF antibody. [Solution] An anti-human CTGF antibody containing a heavy-chain variable region comprising the amino acid sequence represented by SEQ ID NO: 10 and a light-chain variable region comprising the amino acid sequence represented by SEQ ID NO: 4.
申请公布号 WO2013094723(A1) 申请公布日期 2013.06.27
申请号 WO2012JP83206 申请日期 2012.12.21
申请人 ASTELLAS PHARMA INC. 发明人 IWASAKI, SHOJI;MORIYA, RYUICHI;YOSHINO, MASAYASU;TAKAKURA, KOJI
分类号 C12N15/09;C07K16/22;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12P21/08 主分类号 C12N15/09
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