发明名称 |
GENE INACTIVATION ALLOWING IMMEDIATE GROWTH ON XYLOSE MEDIUM BY ENGINEERED ZYMOMONAS |
摘要 |
Zymomonas cells that are genetically engineered to have a disrupted aldose reductase gene such that aldose reductase activity for conversion of xylose to xylitol in the presence of NADPH is reduced by greater than 90%, and that are engineered to express a xylose utilization metabolic pathway, were found to have the ability to gro on medium containing xylose as the only sugar without adaptation in media containing xylose. |
申请公布号 |
CA2859198(A1) |
申请公布日期 |
2013.06.27 |
申请号 |
CA20122859198 |
申请日期 |
2012.12.19 |
申请人 |
E. I. DU PONT DE NEMOURS AND COMPANY |
发明人 |
HITZ, WILLIAM D.;QI, MIN;TAO, LUAN;VIITANEN, PAUL V.;YANG, JIANJUN |
分类号 |
C12N9/00;C12N1/21;C12N9/10;C12N9/12;C12N9/92;C12P7/06;C12P7/10 |
主分类号 |
C12N9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|