| 发明名称 |
BLADDER CANCER TUMOR MARKER, ANTIBODY AND USE THEREOF |
| 摘要 |
Provided in the present invention are an aberrantly glycosylated integrin, AG-alpha3beta1, and use thereof as a bladder cancer marker. Also provided in the present invention are a hybridoma cell generating an anti-AG-alpha3beta1 monoclonal antibody, a monoclonal antibody BCMab1 secreted by the same, and use of BCMab1 in the preparation of a medicament for the treatment of bladder cancer. Also provided in the present invention is use of inhibitors of GAL3ST2 and N-acetylgalactosaminyltransferase 1 in the preparation of a medicament for the treatment of bladder cancer.
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| 申请公布号 |
US2013164216(A1) |
申请公布日期 |
2013.06.27 |
| 申请号 |
US201113814446 |
申请日期 |
2011.08.12 |
| 申请人 |
LI CHONG;FAN ZUSEN;ZHANG HONGLIAN;DAI ZHONGHUA;TANG HAIDONG;CHEN JUN;INSTITUTE OF BIOPHYSICS, CHINESE ACADEMY OF SCIENCES |
发明人 |
LI CHONG;FAN ZUSEN;ZHANG HONGLIAN;DAI ZHONGHUA;TANG HAIDONG;CHEN JUN |
| 分类号 |
C07K14/705;A61K39/395;A61K45/06;A61K47/48;A61K51/10;C07K16/30;C12N15/113;C12Q1/02;C12Q1/48;G01N33/574;G01N33/68 |
主分类号 |
C07K14/705 |
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