发明名称 |
ANTI-NGF ANTIBODIES AND THEIR USE |
摘要 |
The present disclosure encompasses NGF binding proteins, specifically to antibodies that are chimeric, CDR grafted and canonized antibodies, and methods of making and uses thereof. The antibodies, or antibody portions, of the disclosure are useful for detecting NGF and for inhibiting NGF activity, e.g., in a mammal subject suffering from a disorder in which NGF activity is detrimental. |
申请公布号 |
EP2606067(A2) |
申请公布日期 |
2013.06.26 |
申请号 |
EP20110767319 |
申请日期 |
2011.08.19 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
LACEY, SUSAN E.;BARBON, JEFFREY A.;CHHAYA, MEHA;FUNG, EMMA;HUTCHINS, CHARLES W.;LANG, DIANE M.;BARLOW, EVE H.;LEDDY, MARY;CHARI, RAVI |
分类号 |
C07K16/22 |
主分类号 |
C07K16/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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