| 发明名称 |
Process for adenovirus purification from high cell density cultures |
| 摘要 |
The invention provides methods for large-scale adenovirus purification from high cell density suspensions, using host cell DNA fragmentation and/or precipitation followed by a clarification step with tangential flow filtration.
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| 申请公布号 |
US8470585(B2) |
申请公布日期 |
2013.06.25 |
| 申请号 |
US201013501731 |
申请日期 |
2010.10.14 |
| 申请人 |
DE VOCHT MARCEL LEO;VEENSTRA MARLOES;CRUCELL HOLLAND B.V. |
发明人 |
DE VOCHT MARCEL LEO;VEENSTRA MARLOES |
| 分类号 |
C12N1/02;A61K39/00;A61K39/23;C12N15/00 |
主分类号 |
C12N1/02 |
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