发明名称 Optically active cyclic alcohol compound
摘要 The present invention relates to a method for preparing an optically active cyclic alcohol compound represented by general formula [I]: [wherein R represents a hydrogen atom or a protecting group for amino group, and * represents an asymmetric carbon atom.] which comprises a step of subjecting a cyclic ketone compound represented by general formula [II]: [wherein R has the same meaning as defined above.] to asymmetric reduction (A) in the presence of an optically active oxazaborolidine compound and a boron hydride compound, or (B) in the presence of an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand and a hydrogen donor, and relates to said compound.
申请公布号 US8471028(B2) 申请公布日期 2013.06.25
申请号 US201113087588 申请日期 2011.04.15
申请人 OKAMOTO MASAKI;SAKURAGI AKIRA;MORI YOSHIKAZU;KISHIDA MUNEKI;HIGASHIJIMA TAKANORI;MITSUBISHI TANABE PHARMA CORPORATION 发明人 OKAMOTO MASAKI;SAKURAGI AKIRA;MORI YOSHIKAZU;KISHIDA MUNEKI;HIGASHIJIMA TAKANORI
分类号 C07D401/04 主分类号 C07D401/04
代理机构 代理人
主权项
地址