发明名称 |
Optically active cyclic alcohol compound |
摘要 |
The present invention relates to a method for preparing an optically active cyclic alcohol compound represented by general formula [I]: [wherein R represents a hydrogen atom or a protecting group for amino group, and * represents an asymmetric carbon atom.] which comprises a step of subjecting a cyclic ketone compound represented by general formula [II]: [wherein R has the same meaning as defined above.] to asymmetric reduction (A) in the presence of an optically active oxazaborolidine compound and a boron hydride compound, or (B) in the presence of an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand and a hydrogen donor, and relates to said compound.
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申请公布号 |
US8471028(B2) |
申请公布日期 |
2013.06.25 |
申请号 |
US201113087588 |
申请日期 |
2011.04.15 |
申请人 |
OKAMOTO MASAKI;SAKURAGI AKIRA;MORI YOSHIKAZU;KISHIDA MUNEKI;HIGASHIJIMA TAKANORI;MITSUBISHI TANABE PHARMA CORPORATION |
发明人 |
OKAMOTO MASAKI;SAKURAGI AKIRA;MORI YOSHIKAZU;KISHIDA MUNEKI;HIGASHIJIMA TAKANORI |
分类号 |
C07D401/04 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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