摘要 |
Disclosed are a novel thiazole-containing benzophenone derivative represented by formula 1, and an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof and a solvate thereof, a pharmaceutical composition comprising the derivative, a use of the derivative as therapeutic agent and a method for preparing the derivative. The benzophenone thiazole derivatives inhibit formation of microtubules and eliminate actively proliferating cells of malignant tumors to control general cell proliferation. In formula 1, R, R1 and R2 are defined as above.
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申请人 |
CHONG KUN DANG PHARMACEUTICAL CORP. |
发明人 |
CHOI, NAM-SONG;KIM, YOUNG-HOON;LEE, JAE-KWANG;KANG, HEE-RYONG;CHOI, HO-JIN;MOON, SEUNG-KEE;KIM, SOO-JIN;PARK, GYU-TAE;HAN, BYEONG-HOON;KIM, DAL-HYUN;CHOI, JAE-HOON;LEE, SUNG-SOOK;AHN, SOON-KIL;LEE, KYUNG-JOO;BAE, SU-YEAL |