| 发明名称 |
Hydrochloride salts of 8-[{1-(3,5-Bis-trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and preparation process therefor |
| 摘要 |
Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same.
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| 申请公布号 |
US8470842(B2) |
申请公布日期 |
2013.06.25 |
| 申请号 |
US20090614108 |
申请日期 |
2009.11.06 |
| 申请人 |
HU MENGWEI;PALIWAL SUNIL;SHIH NENG-YANG;GUENTER FRANK BRUNO;MERGELSBERG INGRID;OPKO HEALTH, INC. |
发明人 |
HU MENGWEI;PALIWAL SUNIL;SHIH NENG-YANG;GUENTER FRANK BRUNO;MERGELSBERG INGRID |
| 分类号 |
A01N43/42;A61K31/44;C07D215/00;C07D217/00;C07D219/00;C07D221/00 |
主分类号 |
A01N43/42 |
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