发明名称 MICRORNA PER LA RIGENERAZIONE CARDIACA ATTRAVERSO L INDUZIONE DELLA PROLIFERAZIONE DEI MIOCITI CARDIACI
摘要 The present invention discloses a set of human microRNAs, or a primary transcript for such microRNAs, or a precursor of such microRNAs, or a mimic of such microRNAs or a combination thereof, and their use as medicaments for inducing proliferation of cardiomyocytes for the prevention and treatment of heart diseases associated with a loss of cardiomyocytes. The invention also relates to a method for screening microRNAs and biological and therapeutically active compounds for their ability to increase proliferation of cardiomyocytes.
申请公布号 ITRM20110685(A1) 申请公布日期 2013.06.24
申请号 IT2011RM00685 申请日期 2011.12.23
申请人 INTERNATIONAL CENTRE FOR GENETIC EN GINEERING AND 发明人 BREGIEIRO EULALIO ANA SOFIA;CUNHA MANO MIGUEL LUIS;GIACCA MAURO;ZACCHIGNA SERENA
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