发明名称 |
GENERAL STRATEGY FOR ANTIBODY LIBRARY SCREENING |
摘要 |
A generally applicable method for the selective covalent attachment of a reporter molecule to a replicating entity that allows one to obtain specific binders from a single round of library screening is disclosed. For example, selective biotinylation of phage particles and yeast cells displaying a binder to any given target can be achieved via application of a coupled enzyme reaction that includes a peroxidase, an oxidase and a catalase. |
申请公布号 |
WO2013087215(A1) |
申请公布日期 |
2013.06.20 |
申请号 |
WO2012EP05162 |
申请日期 |
2012.12.14 |
申请人 |
MERCK PATENT GMBH |
发明人 |
BECKER, STEFAN;HEISELER, TIM;SCHUMACHER, ALEXANDER;KOLMAR, HARALD |
分类号 |
G01N33/532;C12N15/10;G01N33/542 |
主分类号 |
G01N33/532 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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