摘要 |
The present invention provides a combination of urea and isoleucine as active ingredients for sequential, simultaneous or separate administration for use in the prevention and/or treatment of a cutaneous disorder which benefits from an enhancement in the production of endogenous antimicrobial peptides in the skin. The invention further provides topical compositions comprising an effective amount of a combination of urea and isoleucine, wherein both urea and isoleucine act as active ingredients. |