摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to tetraazaphenalen-3-one compounds, particularly a compound of formulawhich inhibit poly(ADP-ribose)polymerase (PARP) and may be used for chemosensitisation in relation to anticancer chemotherapeutic agents.EFFECT: higher effectiveness of the chemotherapeutic agents, and in treating cancer diseases characterised by the DNA repair defects.13 cl, 2 tbl, 6 dwg, 3 ex |