| 发明名称 |
TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS |
| 摘要 |
Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.
|
| 申请公布号 |
US2013157996(A1) |
申请公布日期 |
2013.06.20 |
| 申请号 |
US201213529860 |
申请日期 |
2012.06.21 |
| 申请人 |
BISWAS KAUSTAV;BROWN JAMES;CHEN JIAN J.;GORE VIJAY KESHAV;HARRIED SCOTT;HORNE DANIEL B.;KALLER MATTHEW R.;LIU QINGYIAN;MA VU VAN;MONENSCHEIN HOLGER;NGUYEN THOMAS T.;ST. JEAN, JR. DAVID J.;YUAN CHESTER CHENGUANG;ZHONG WENGE;AMGEN INC. |
发明人 |
BISWAS KAUSTAV;BROWN JAMES;CHEN JIAN J.;GORE VIJAY KESHAV;HARRIED SCOTT;HORNE DANIEL B.;KALLER MATTHEW R.;LIU QINGYIAN;MA VU VAN;MONENSCHEIN HOLGER;NGUYEN THOMAS T.;ST. JEAN, JR. DAVID J.;YUAN CHESTER CHENGUANG;ZHONG WENGE |
| 分类号 |
C07D498/04;C07D213/81;C07D401/12;C07D401/14;C07D413/12;C07D471/04;C07D487/04 |
主分类号 |
C07D498/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
