发明名称 Peptide compounds for capturing or inhibiting Avian Influenza virus and application thereof
摘要 Agent (I) comprises peptide compounds (II). Agent (I) comprises peptide compounds of formula (X-(hHN-HC(R)-C(=O)) m-(O)-X1) (II). X, X1 : H, a functional group of biotin, streptavidin or avidin, a functional moiety composed of a functional group of biotin, streptavidin or avidin, or a linker which connects the functional group to a backbone of (II); m : 2-10; n : 0-1; and R : H, -CH 3, -CH(CH 3) 2, -CH 2CH(CH 3) 2, -CHCH 3CH 2CH 3, -CH 2OH, -CHOH-CH 3, -CH 2SH, -(CH 2) 2SCH 3, -CH 2COOH, -CH 2CONH 2, -(CH 2) 2COOH, -(CH 2) 2CONH 2, -(CH 2) 3CH 2NH 2, -(CH 2) 3NHC-NHNH 2, 5-methyl-1H-imidazole, benzyl, 4-methyl phenol, 3-methyl-1H indole, -CH 2-CH 2-CH 2 or CH 2SSCH 2-. Independent claims are included for: (1) the peptide compounds (II), with a proviso that X and X1 are not H at the same time; (2) detecting avian influenza virus comprising contacting (II) with a sample to be tested; and (3) a biosensor for diagnosing avian influenza infection, comprising (I) as a detector or capturer of avian influenza virus. - ACTIVITY : Virucide. - MECHANISM OF ACTION : Avian influenza virus H5 protein binder. Test details are described but no results given.
申请公布号 KR101277272(B1) 申请公布日期 2013.06.20
申请号 KR20090095680 申请日期 2009.10.08
申请人 发明人
分类号 A61K47/42;C07K1/00;C07K7/06;G01N33/569 主分类号 A61K47/42
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