发明名称 |
METHOD FOR IDENTIFYING HETERO-MULTIMERIC MODIFIED UBIQUITIN PROTEINS WITH BINDING CAPABILITY TO LIGANDS |
摘要 |
The present invention refers to a method for identifying hetero-multimeric ubiquitins with binding capability to a ligand. Furthermore, the invention provides DNA libraries encoding for a population of said hetero-multimeric ubiquitins as well as protein libraries obtained by expression of said DNA libraries, cells and phages containing said DNA or proteins, polynucleotides encoding for said fusion proteins and vectors comprising said polynucleotides. Further new binding proteins based on hetero-multimeric ubiquitin being able to bind specifically with high affinity to selected ligands are provided. |
申请公布号 |
US2013157878(A1) |
申请公布日期 |
2013.06.20 |
申请号 |
US201013144809 |
申请日期 |
2010.12.14 |
申请人 |
KUNERT ANJA;NARKAMP JOERG;STEUERNAGEL ARND;FIEDLER MARKUS;FIEDLER ERIK;GOETTLER THOMAS |
发明人 |
KUNERT ANJA;NARKAMP JOERG;STEUERNAGEL ARND;FIEDLER MARKUS;FIEDLER ERIK;GOETTLER THOMAS |
分类号 |
C40B30/04;C12N15/62;C12N15/63;C40B40/02;C40B40/06;C40B40/10;G01N33/566 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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