SUBSTITUTED TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

摘要

The present invention provides a novel compound that has P2X3 and/or P2X2/3 receptor antagonist activity, for example, a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. (In the formula, Ra and Rb as well as Rd and Re are both hydrogen atoms or the like; Rc represents a hydrogen atom or the like; each of R4a and R4b represents a hydrogen atom or the like; n represents 1 or the like; R2 represents a cycloalkyl group or the like; each of -X- and -L- represents -O-, -S- or the like; ring D represents a benzene ring or the like; carbon atoms a and b are carbon atoms; ring B represents an aromatic carbon ring or the like; each of s and s' represents 0 or the like; and each of R9 and R9' represents a halogen group or the like.)