摘要 |
<P>PROBLEM TO BE SOLVED: To provide neurokinin-1 (NK-I) receptor antagonists, and inhibitors of tachykinin and in particular substance P, used in the treatment of emesis, urinary incontinence, LUTS, depression, and anxiety. <P>SOLUTION: The present invention is directed to certain hydroxymethyl ether hydroisoindoline compounds of Formula (I). <P>COPYRIGHT: (C)2013,JPO&INPIT |