发明名称 |
Compositions Using Antibodies Directed To GPNMB And Uses Thereof |
摘要 |
The present invention relates to antibodies, including fully human monoclonal antibodies, with specificity to GPNMB, and uses of such antibodies. The present invention further provides compositions that increase expression of GPNMB on the surface of tumor cells, and methods of using such compositions to increase the anti-cancer activity or other therapeutic efficacy of the antibodies and immunoconjugates provided herein.
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申请公布号 |
US2013156784(A1) |
申请公布日期 |
2013.06.20 |
申请号 |
US201213544526 |
申请日期 |
2012.07.09 |
申请人 |
JEFFERS MICHAEL;LAROCHELLE WILLIAM |
发明人 |
JEFFERS MICHAEL;LAROCHELLE WILLIAM |
分类号 |
A61K39/395;A61K31/35;A61K31/426;A61K31/4439;A61K31/4706;A61K31/5025;A61K31/506;A61K33/20;A61K45/06 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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