发明名称 POLYPEPTIDE COMPRISING THE SEQUENCE EGPWLEEEEEAYG LINKED TO AN IMMUNOGENIC CARRIER
摘要 The present invention provides a compound comprising a polypeptide conjugated to an immunogenic carrier, the polypeptide comprising the sequence EGPWLEEEEEAYG (SEQ ID NO: 1) and having fewer than 17 amino acid residues, for use in medicine. Further, the invention provides a compound comprising a polypeptide conjugated to an immunogenic carrier, the polypeptide comprising the sequence EGPWLEEEEEAYG (SEQ ID NO: 1) and having fewer than 17 amino acid residues, wherein the immunogenic carrier is diphtheria toxoid, tetanus toxoid, keyhole limpet haemocyanin, Purified protein derivative (PPD), Albumin, and/or viral proteins. The polypeptide may be conjugated to the immunogenic carrier via a cysteine residue. Pharmaceutical compositions and kits of parts are also provided. In particular, the use of the compounds in medicine and in the treatment of cancer is provided.
申请公布号 WO2013088141(A1) 申请公布日期 2013.06.20
申请号 WO2012GB53105 申请日期 2012.12.12
申请人 ASTRIMMUNE LIMITED 发明人 STEVENS, VERNON;BROOME, PAUL
分类号 A61K47/48;A61P35/00;C07K7/08;C07K14/595 主分类号 A61K47/48
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