| 发明名称 |
4-(4-BROMOPHENYL)-4-OXO-2-{[3-ETHOXYCARBONYL)-4,5-DIMETHYLTHIEN-2-YL]AMINO}-2-BUTENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY |
| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry and specifically to novel biologically active substances of the class of 4-aryl-2,4-dioxobutanoic acids. Disclosed is 4-(4-bromophenyl)-4-oxo-2-{[3-ethoxycarbonyl)-4,5-dimethylthien-2-yl]amino}-2-butenoic acid, having anti-inflammatory and analgesic activity, of formula (1):.EFFECT: obtaining a compound with high output, having marked anti-inflammatory and analgesic activity as well as low toxicity.1 cl, 1 tbl |
| 申请公布号 |
RU2485112(C1) |
申请公布日期 |
2013.06.20 |
| 申请号 |
RU20120117171 |
申请日期 |
2012.04.26 |
| 申请人 |
FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "PERMSKIJ GOSUDARSTVENNYJ NATSIONAL'NYJ ISSLEDOVATEL'SKIJ UNIVERSITET" |
发明人 |
MAKHMUDOV RAMIZ RAGIBOVICH;RUBTSOV ALEKSANDR EVGEN'EVICH;SHIPILOVSKIKH SERGEJ ALEKSANDROVICH |
| 分类号 |
C07D333/38;A61K31/381;A61P29/00 |
主分类号 |
C07D333/38 |
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