发明名称 SELECTIVE EP4 RECEPTOR AGONISTIC SUBSTANCE FOR TREATMENT OF CANCER
摘要 <p>This invention provides a medicament for the treatment of cancer, which cause a reduction of cancer. This invention relates to use of a compound which has inhibitory activities against prostaglandin E2 receptor (EP4 receptor) and is represented by the following general formula (I), (II), (III), or (IV), or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt for the manufacture of a medicament for the treatment of cancer. The invention relates to a method for treatment of cancer comprising administering the compound or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt to humans or animals. The compound or a pharmaceutically acceptable salt thereof, or the pharmaceutical composition may be used in combination with one or more second active agents.</p>
申请公布号 EP2422779(A4) 申请公布日期 2013.06.19
申请号 EP20100767106 申请日期 2010.04.22
申请人 RAQUALIA PHARMA INC 发明人 TAKE, YUKINORI;KOIZUMI, SHINICHI;OKUMURA, TAKAKO;NONOMURA, KAZUHIKO
分类号 A61K31/192;A61K31/437;A61K31/4412;A61P35/00;A61P43/00;C07D213/64;C07D471/04 主分类号 A61K31/192
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