发明名称 |
METHOD OF INDUCING DIFFERENTIATION FROM PLURIPOTENT STEM CELLS TO GERM CELLS |
摘要 |
<p>This invention provides a method of producing an epiblast-like cell (EpiLC) from a pluripotent stem cell, which comprises culturing the pluripotent stem cell in the presence of activin A; a method of producing a primordial germ cell-like (PGC-like) cell a pluripotent stem cell, which comprises culturing the EpiLC obtained by the method above in the presence of BMP4 and LIF. Also provided are a cell population containing PGC-like cells as obtained by the method, and reagent kits for the EpiLC- and PGC-like cell-induction from a pluripotent stem cell.</p> |
申请公布号 |
EP2603583(A1) |
申请公布日期 |
2013.06.19 |
申请号 |
EP20110816353 |
申请日期 |
2011.07.28 |
申请人 |
KYOTO UNIVERSITY |
发明人 |
SAITOU, MITINORI;HAYASHI, KATSUHIKO |
分类号 |
C12N5/10;C12N5/071;C12N5/073;C12N5/0735 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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