发明名称 |
ACTRIIB PROTEINS AND VARIANTS AND USES THEREFORE RELATING TO UTROPHIN INDUCTION FOR MUSCULAR DYSTROPHY THERAPY |
摘要 |
In certain aspects, the present invention provides compositions and methods for inducing utrophin expression in muscle with an ActRIIB protein as therapy for muscular dystrophy. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand. |
申请公布号 |
EP2501400(A4) |
申请公布日期 |
2013.06.19 |
申请号 |
EP20100832122 |
申请日期 |
2010.11.17 |
申请人 |
ACCELERON PHARMA, INC. |
发明人 |
SEEHRA, JASBIR;LACHEY, JENNIFER |
分类号 |
A61K38/18 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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