| 摘要 |
<p>The present invention relates to a process for making the compound 3-(3-fluoro-4-(morpholin-4-yl)phenyl)-2-oxooxazolidin-5(S)-ylmethyl)amine of formula (II) and/or an acid addition salt thereof comprising b) reacting the compound of formula (VII) wherein L is a leaving group, with a metal salt of diformylamide of formula (VIII) wherein Me+ is a sodium or potassium cation, b) subjecting the reaction product of the step (a) comprising, alone or in admixture, compounds of formula (IXa) and/or (IXb), to a reaction with an acid, and to the making of linezolid by acetylation of the compound of formula (II).</p> |
