发明名称 POSITIVE ALLOSTERIC MODULATORS OF MGLUR2
摘要 The present invention is directed to benzimidazolone derivatives which are positive allosteric modulators of the mGluR2 receptor, useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 receptor is involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved, such as schizophrenia.
申请公布号 EP2603079(A1) 申请公布日期 2013.06.19
申请号 EP20110816846 申请日期 2011.08.05
申请人 MERCK SHARP & DOHME CORP. 发明人 DUDKIN, VADIM;FRALEY, MARK, E.;ARRINGTON, KENNETH, L.;LAYTON, MARK, E.;RODZINAK, KEVIN, J.;PERO, JOSEPH, E.;REIF, ALEXANDER, J.
分类号 C07D401/14;A01N43/50;A61K31/415;C07D235/26;C07D401/04;C07D401/06;C07D401/10;C07D401/12;C07D403/04;C07D403/10;C07D405/06;C07D405/10;C07D409/10;C07D413/10;C07D417/14;C07D453/02;C07D471/04;C07D513/14 主分类号 C07D401/14
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