发明名称 |
EXOGENOUSLY TRIGGERED CONTROLLED RELEASE MATERIALS AND USES THEREOF |
摘要 |
The disclosure provides cross-linked materials that include multivalent cross-linking agents that bind an exogenous target molecule; and conjugates that include two or more separate affinity ligands bound to a conjugate framework, wherein the two or more affinity ligands compete with the exogenous target molecule for binding with the cross-linking agents and wherein conjugates are cross-linked within the material as a result of non-covalent interactions between cross-linking agents and affinity ligands on different conjugates. The conjugates also include a drug. |
申请公布号 |
EP2391216(A4) |
申请公布日期 |
2013.06.19 |
申请号 |
EP20100736336 |
申请日期 |
2010.01.27 |
申请人 |
SMARTCELLS, INC. |
发明人 |
ZION, TODD, C.;LANCASTER, THOMAS, M. |
分类号 |
C07K14/62;A61K38/28;A61K47/48 |
主分类号 |
C07K14/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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