| 摘要 |
PURPOSE: An antibiotic peptide with a simple constitution and short length is provided to ensure strong antibacterial property and to be used as a candidate substance for developing novel antibiotics. CONSTITUTION: A peptide with antibiotic activity contains sequence numbers 1-12. A pharmaceutical composition contains the peptide as an active ingredient. An antibacterial composition against microorganism contains the peptide as an active ingredient. The peptide contains an amino acid sequence of sequence number 9 or 10. The microorganism is a gram positive or gram negative bacteria. The gram positive bacteria are subtilis, Staphylococcus aureus, Staphylococcus epidermis, Micrococcus luteus, or MRSA(methicillin-resistant Staphylococcus aureus). The gram negative bacteria are Escherichia coli, Shigella dysentariae, Salmonella typhomurium, Klebsiella pneumoniae, or Pseudomonas aeruginosa. |
