发明名称 |
4-AMINOQUINAZOLIN-2-YL-1-PYRRAZOLE-4-CARBOXYLIC ACID COMPOUNDS AS PROLYL HYDROXYLASE INHIBITORS |
摘要 |
Aminoquinazolinyl compounds of formula (I) are described, which are useful as prolyl hydroxylase inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by prolyl hydroxylase activity. Thus, the compounds may be administered to treat, e.g., anemia, vascular disorders, metabolic disorders, and wound healing. |
申请公布号 |
EP2603502(A1) |
申请公布日期 |
2013.06.19 |
申请号 |
EP20110749643 |
申请日期 |
2011.08.12 |
申请人 |
JANSSEN PHARMACEUTICA, N.V. |
发明人 |
RABINOWITZ, MICHAEL, H.;ROSEN, MARK, D.;TARANTINO, KYLE, T.;VENKATESAN, HARIHARAN |
分类号 |
C07D403/04;A61K31/517;A61K31/55;A61P3/10;A61P9/00;C07D403/14;C07D405/14;C07D413/14;C07D417/14 |
主分类号 |
C07D403/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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