<p>A method of diagnosing Alzheimer's disease in a subject comprising: a) determining and/or characterizing the telomeric organization of cells in a test sample from the subject; wherein a difference in the telomeric organization, for example the number and/or length of telomeres in the test sample cells compared to a control is indicative the subject has Alzheimer's disease or an increased risk of developing Alzheimer's disease.</p>
