发明名称 |
Compositions of a peptide targeting system for treating cancer |
摘要 |
<p>This invention describes a protein nanoparticle system for targeting siRNA or other drugs into tumors. The basis of the protein system is elastin-like peptides that self-assemble once exposed to the nucleic acid of the siRNA. Specific targeting peptides are fused to the core ELP structure by standard genetic engineering techniques. These targeting peptides confer specific binding of the nanoparticle to receptors on the surface of tumor cells and allow for uptake of the nanoparticle into the tumor cells.</p> |
申请公布号 |
AU2011323508(A1) |
申请公布日期 |
2013.06.13 |
申请号 |
AU20110323508 |
申请日期 |
2011.11.01 |
申请人 |
PEPTIMED, INC. |
发明人 |
PRIMIANO, THOMAS;CHANG, BEY-DIH;HEIDEL, JEREMY |
分类号 |
C07K14/78;A61K47/48;A61K48/00;A61P35/00;C12N15/87 |
主分类号 |
C07K14/78 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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