| 发明名称 |
PEGYLATED ASPARTYL-TRNA SYNTHETASE POLYPEPTIDES |
| 摘要 |
<p>The present invention provides PEGylated aspartyl-tRNA synthetase (DRS) polypeptides, compositions comprising the same, and methods of using such polypeptides and compositions for treating or diagnosing a variety of conditions. The PEGylated DRS polypeptides of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic properties compared to non-PEGylated DRS polypeptides.</p> |
| 申请公布号 |
WO2013086228(A1) |
申请公布日期 |
2013.06.13 |
| 申请号 |
WO2012US68296 |
申请日期 |
2012.12.06 |
| 申请人 |
ATYR PHARMA, INC. |
发明人 |
BUECHLER, YING JI;WU, CHI-FANG;GREVE, JEFFREY;MENDLEIN, JOHN D. |
| 分类号 |
C12N15/52;A61K38/43;A61P35/00 |
主分类号 |
C12N15/52 |
| 代理机构 |
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