| 发明名称 |
MULTICOMPONENT CRYSTALLINE SYSTEM OF VORICONAZOLE WITH FUMARIC ACID |
| 摘要 |
<p>A novel solid form of Voriconazole comprises the active ingredient (2R,3S)-2-(2,4- difluorophenyl)- 3-(5-fluoropyrimidin- 4-yl)-1 -(1H-1,2,4-triazol-1 -yl)butan-2-ol and fumaric acid. The solid composition comprising the two components shows improved properties such as water solubility, crystallization behavior and stability.</p> |
| 申请公布号 |
CA2858316(A1) |
申请公布日期 |
2013.06.13 |
| 申请号 |
CA20122858316 |
申请日期 |
2012.12.03 |
| 申请人 |
BASF SE |
发明人 |
HAFNER, ANDREAS;HINTERMANN, TOBIAS;BLATTER, FRITZ;RODEL, EVA |
| 分类号 |
C07D403/10;A61K31/506;A61P31/10 |
主分类号 |
C07D403/10 |
| 代理机构 |
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