发明名称 |
USE OF COMPOUNDS WITH THROMBOPOIETIC ACTIVITY TO PROMOTE BONE GROWTH AND HEALING |
摘要 |
TPO was used to promote the growth of bone in both rats and in mice. Gaps in both mouse and in rat bones were treated with a scaffold sized to fit the gap. Scaffolds that included TPO promoted better outcomes than scaffolds that included BMP-2 or scaffolds that did not include either TPO or BMP-2. These data indicate that compounds that exhibit thrombopoietic activity such a recombinant TPO can be used to promote bone growth and healing in mammals.
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申请公布号 |
US2013149349(A1) |
申请公布日期 |
2013.06.13 |
申请号 |
US201113700904 |
申请日期 |
2011.06.03 |
申请人 |
KACENA MELISSA A.;CHU TIEN-MIN GABRIEL;INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION |
发明人 |
KACENA MELISSA A.;CHU TIEN-MIN GABRIEL |
分类号 |
A61L27/54 |
主分类号 |
A61L27/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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