IODINE-CONTAINING RADIAL-SHAPED MACROMOLECULAR COMPOUNDS, PREPARATION METHOD THEREOF AND CONTRAST MEDIA COMPOSITIONS FOR CT COMPRISING THE SOME

摘要

Disclosed herein is an iodine-containing radial-shaped macromolecule suitable for an active ingredient of the computed tomography (CT) contrast medium, a method to prepare the same, and a contrast medium composition including the same. With respect to the iodine-containing radial-shaped macromolecule according to the present invention, the duration of contrast enhancement has been significantly improved in comparison to that of the current small molecular contrast media compounds containing iodine.