摘要 |
<P>PROBLEM TO BE SOLVED: To provide a compound useful for therapy of spinal muscular atrophy. <P>SOLUTION: The compound is represented by a structural formula expressed by formulae I and II, where in formulae, W represents C(O), C(S) and CH<SB POS="POST">2</SB>; B represents CH<SB POS="POST">2</SB>or CH(C<SB POS="POST">n</SB>H<SB POS="POST">2n+1</SB>) (n is 1 to 8); C represents a condensed thiophene ring, a condensed pyridine ring, a cyclohexane ring, etc.; R<SB POS="POST">1</SB>and R<SB POS="POST">2</SB>each represents H, 1-3C alkyl etc.; R<SB POS="POST">3</SB>represents H, halogen, 1-4C alkyl etc.: R<SB POS="POST">4</SB>, R<SB POS="POST">5</SB>, R<SB POS="POST">6</SB>and R<SB POS="POST">7</SB>each represents H, hydroxy, halogen, CN etc.; and X represents H, CN etc. <P>COPYRIGHT: (C)2013,JPO&INPIT |