发明名称 COMPOUND FOR THERAPY OF SPINAL MUSCULAR ATROPHY AND OTHER APPLICATION
摘要 <P>PROBLEM TO BE SOLVED: To provide a compound useful for therapy of spinal muscular atrophy. <P>SOLUTION: The compound is represented by a structural formula expressed by formulae I and II, where in formulae, W represents C(O), C(S) and CH<SB POS="POST">2</SB>; B represents CH<SB POS="POST">2</SB>or CH(C<SB POS="POST">n</SB>H<SB POS="POST">2n+1</SB>) (n is 1 to 8); C represents a condensed thiophene ring, a condensed pyridine ring, a cyclohexane ring, etc.; R<SB POS="POST">1</SB>and R<SB POS="POST">2</SB>each represents H, 1-3C alkyl etc.; R<SB POS="POST">3</SB>represents H, halogen, 1-4C alkyl etc.: R<SB POS="POST">4</SB>, R<SB POS="POST">5</SB>, R<SB POS="POST">6</SB>and R<SB POS="POST">7</SB>each represents H, hydroxy, halogen, CN etc.; and X represents H, CN etc. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013116901(A) 申请公布日期 2013.06.13
申请号 JP20130004082 申请日期 2013.01.11
申请人 USA GOVERNMENT;ALBANY MOLECULAR RESEARCH INC 发明人 HEEMSKERK JILL;BARNES KEITH D;MCCALL JOHN M;JOHNSON GRAHAM;FAIRFAX DAVID;JOHNSON MATTHEW ROBERT
分类号 C07D209/46;A61K31/4035;A61K31/407;A61K31/437;A61K31/4439;A61K31/454;A61K31/506;A61K31/5377;A61P3/10;A61P9/10;A61P13/12;A61P21/02;A61P21/04;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P31/00;A61P31/12;A61P31/18;A61P35/00;A61P43/00;C07D401/04;C07D401/10;C07D403/04;C07D403/10;C07D407/10;C07D409/04;C07D409/10;C07D471/04;C07D491/056;C07D495/04 主分类号 C07D209/46
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