The present invention includes embodiments for treatment and/or prevention of sickle cell disease that employ Hydroxyfasudil or Isocoronarin D alone or either in conjunction with each other or an inducer of HbF production. The compounds may act synergistically, and the compounds employed circumvent the side effects seen with Hydroxyurea.
申请公布号
WO2013057592(A3)
申请公布日期
2013.06.13
申请号
WO2012IB02887
申请日期
2012.09.13
申请人
KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY;ESSACK, MAGBUBAH;BAJIC, VLADIMIR;RADOVANOVIC, ALEKSANDAR
发明人
ESSACK, MAGBUBAH;BAJIC, VLADIMIR;RADOVANOVIC, ALEKSANDAR