Composition comprising cinnamoylsalcylamide derivatives or the pharmaceutically acceptable salt thereof for treating or preventing cancer disease

摘要

PURPOSE: A composition containing cinnamoylsalcylamide derivatives and pharmaceutically acceptable salts thereof is provided to strongly suppress Wint signal transduction and to prevent and treat cancer. CONSTITUTION: A pharmaceutical composition for preventing and treating cancer contains cinnamoylsalcylamide derivatives of general formula I, II, or III, or pharmaceutically acceptable salts thereof as an active ingredient. The cinnamoylsalcylamide derivative is an N-[3-benzo[1,3]deoxole-1-oxo-2-prophenyl]-2-hydroxybenzamide(YJ13) compound group or an N-[3-thiophene-1-oxo-2-prophenyl]-2-hydroxybenzamide(YJ24) compound group. A Wint signal transduction inhibitor contains the cinnamoylsalcylamide derivative or salts as an active ingredient.