摘要 |
<p>In one aspect of the invention, an integrated bio-object micro fluidics chip includes a fluidic network having a plurality of inlets for providing a plurality of fluids, a plurality of outlets, a bio-object chamber for accommodating at least one bio- object, a plurality of fluidic switches, and one or more pumps, coupled to each other such that at least one fluidic switch operably and selectively receives one fluid from a corresponding inlet and routes the received fluid, through the one or more pumps, to the bio-object chamber so as to perfuse the at least one bio-object therein, and one of the downstream fluidic switches selectively delivers an effluent of the at least one bio-object responsive to the perfusion to a predetermined outlet destination, or to the at least one fluidic switch for recirculation.</p> |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
WIKSWO, JOHN, P.;CLIFFEL, DAVID, E.;MARKOV, DMITRY, A.;MCLEAN, JOHN, A.;MCCAWLEY, LISA, JOY;SAMSON, PHILLIP, C.;REISERER, RONALD, S.;BLOCK, FRANK, EMMANUEL;MCKENZIE, JENNIFER, ROBIN |