摘要 |
<P>PROBLEM TO BE SOLVED: To provide protease variants having altered flushing capacity obtained by DNA sequences of naturally-occurring or recombinant non-human proteases. <P>SOLUTION: The protease variant includes an amino acid sequence having substitution in one or more residue positions equivalent to residue positions selected from the group consisting of 7, 23, 26, 28, 29, 30, 31, 47, 66, 69, 73, 82, 85, 88, 90, 92, 93, 105, 113, 139, 148, 149, 150, 151, 178, 200, 201, 231, 233, 267 and/or 273 of Bacillus amyloliquefaciens subtilisin. <P>COPYRIGHT: (C)2013,JPO&INPIT |