<p>An anastomosis system for performing anastomosis of a distal lumen with a proximal lumen is described. In one alternative the system includes an anastomosis element having a sensor assembly incorporated therein, the sensor assembly configured to sense the site of anastomosis. In another alternative the system includes an anastomosis component for performing anastomosis of a distal lumen with a proximal lumen; an applicator for applying the anastomosis component; and a sensor assembly connected to the applicator.</p>