发明名称 |
LABELED ALGINATE CONJUGATES FOR MOLECULAR IMAGING APPLICATIONS |
摘要 |
Described are bifunctional NOTA-based derivatives capable of conjugating with alginate and with metal ions, as well as NOTA-alginate conjugates which can be labeled with stable or radioactive metal ions. Also described are conjugation methods of the bifunctional NOTA-based linker with alginate, and methods of using radiometal-labeled NOTA-alginate conjugates or other radio-labeled alginate conjugates as imaging reagents. |
申请公布号 |
WO2013086396(A1) |
申请公布日期 |
2013.06.13 |
申请号 |
WO2012US68546 |
申请日期 |
2012.12.07 |
申请人 |
IKARIA DEVELOPMENT SUBSIDIARY ONE LLC |
发明人 |
RUAN, FUQIANG;DECKWERTH, THOMAS L.;MEGLASSON, MARTIN D. |
分类号 |
C07D255/02 |
主分类号 |
C07D255/02 |
代理机构 |
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代理人 |
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地址 |
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