发明名称 TUMOR-SPECIFC GM-CSF CYTOKINE RESPONSE AS PREDICTOR OF CANCER VACCINE EFFECTIVENESS
摘要 The present invention relates to methods of treating cancer with a cancer vaccine using granulocyte-macrophage colony-stimulating factor (GM-CSF) as a biomarker; methods of prognosticating an outcome of cancer treatment with a cancer vaccine using GM-CSF as a biomarker; methods for qualifying subjects for cancer vaccination using GM-CSF as a biomarker; methods for comparing the efficacy of two or more cancer vaccine treatments based on GM-CSF response; and kits for the effective treatment of cancer.
申请公布号 WO2013086418(A1) 申请公布日期 2013.06.13
申请号 WO2012US68574 申请日期 2012.12.07
申请人 BIOVEST INTERNATIONAL, INC.;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY ,DEPARTMENT OF HEALTH AND HUMAN SERVICES 发明人 WILSON, WYNDHAM, H.;SANTOS, CARLOS;KWAK, LARRY, W.;NEELAPU, SATTVA, S.
分类号 A61K39/395;A61K47/30;A61K47/48;A61P35/00 主分类号 A61K39/395
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