TUMOR-SPECIFC GM-CSF CYTOKINE RESPONSE AS PREDICTOR OF CANCER VACCINE EFFECTIVENESS
摘要
The present invention relates to methods of treating cancer with a cancer vaccine using granulocyte-macrophage colony-stimulating factor (GM-CSF) as a biomarker; methods of prognosticating an outcome of cancer treatment with a cancer vaccine using GM-CSF as a biomarker; methods for qualifying subjects for cancer vaccination using GM-CSF as a biomarker; methods for comparing the efficacy of two or more cancer vaccine treatments based on GM-CSF response; and kits for the effective treatment of cancer.
申请公布号
WO2013086418(A1)
申请公布日期
2013.06.13
申请号
WO2012US68574
申请日期
2012.12.07
申请人
BIOVEST INTERNATIONAL, INC.;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY ,DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人
WILSON, WYNDHAM, H.;SANTOS, CARLOS;KWAK, LARRY, W.;NEELAPU, SATTVA, S.