发明名称 |
EPISOMAL REPROGRAMMING WITH CHEMICALS |
摘要 |
Methods and composition of induction of pluripotent stem cells are disclosed. For example, in certain aspects methods for generating essentially vector-free induced pluripotent stem cells with cell signaling regulators are described. Furthermore, certain aspects of the invention provide novel compositions comprising induced pluripotent stem cells essentially free of exogenous retroviral vector elements in the presence of a medium comprising signaling inhibitors. In certain aspects, feeder-free episomal reprogramming methods may be provided. |
申请公布号 |
EP2496689(A4) |
申请公布日期 |
2013.06.12 |
申请号 |
EP20100829086 |
申请日期 |
2010.11.04 |
申请人 |
CELLULAR DYNAMICS INTERNATIONAL, INC. |
发明人 |
YU, JUNYING |
分类号 |
C12N5/074;C12N5/02;C12N15/85 |
主分类号 |
C12N5/074 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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