发明名称 |
L-fucose alpha1->6 specific lectin |
摘要 |
Disclosed is a novel lectin which can bind specifically to an L-fucose alpha1->6 sugar chain. Also disclosed is use of the lectin. The L-fucose alpha1->6 specific lectin of the present invention is characterized in that: (1) the lectin is extracted from a basidiomycete or an ascomycete; (2) the lectin has a molecular weight by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of 4,000 to 40,000; and (3) the lectin has an affinity to an L-fucose alpha1->6 sugar chain, the affinity being represented by an association constant of 1.0×104M-1 or more (at 25 degrees C.). The lectin can be used for detecting an L-fucose alpha1->6 sugar chain specifically, and is effective for the purification of an L-fucose alpha1->6 sugar chain or a non L-fucose alpha1->6 sugar chain.
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申请公布号 |
US8461305(B2) |
申请公布日期 |
2013.06.11 |
申请号 |
US200913054940 |
申请日期 |
2009.07.15 |
申请人 |
KOBAYASHI YUKA;HIRABAYASHI JUN;TATENO HIROAKI;KAWAGISHI HIROKAZU;DOHRA HIDEO;J-OIL MILLS, INC.;NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCEAND TECHNOLOGY;NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY |
发明人 |
KOBAYASHI YUKA;HIRABAYASHI JUN;TATENO HIROAKI;KAWAGISHI HIROKAZU;DOHRA HIDEO |
分类号 |
C07K16/00 |
主分类号 |
C07K16/00 |
代理机构 |
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主权项 |
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地址 |
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