发明名称 |
Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins |
摘要 |
The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) directed against an intracellular target and having an isoelectric point of at least 8.5, for targeting said intracellular target or for the preparation of a peptide vector. Particularly, it concerns VHH domains directed against a glial fibrillary acidic protein and uses thereof for preparing therapeutic or diagnostic agents.
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申请公布号 |
US8460888(B2) |
申请公布日期 |
2013.06.11 |
申请号 |
US200913002910 |
申请日期 |
2009.07.07 |
申请人 |
LAFAYE PIERRE;BOURGEOIS JEAN-PIERRE;ROUGEON FRANCOIS;INSTITUT PASTEUR |
发明人 |
LAFAYE PIERRE;BOURGEOIS JEAN-PIERRE;ROUGEON FRANCOIS |
分类号 |
G01N33/567;A61K39/395;C07K16/18;C07K16/28 |
主分类号 |
G01N33/567 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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