| 发明名称 |
Mosaic protein and nucleic acid vaccines against hepatitis C virus |
| 摘要 |
The invention relates to immunogenic compositions useful as HCV vaccines. Provided are HCV mosaic polypeptide and nucleic acid compositions which provide higher levels of T-cell epitope coverage while minimizing the occurrence of unnatural and rare epitopes compared to natural HCV polypeptides and consensus HCV sequences.
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| 申请公布号 |
US8460672(B1) |
申请公布日期 |
2013.06.11 |
| 申请号 |
US20100893731 |
申请日期 |
2010.09.29 |
| 申请人 |
YUSIM KARINA;KORBER BETTE T. M.;KUIKEN CARLA L.;FISCHER WILLIAM M.;LOS ALAMOS NATIONAL SECURITY, LLC |
发明人 |
YUSIM KARINA;KORBER BETTE T. M.;KUIKEN CARLA L.;FISCHER WILLIAM M. |
| 分类号 |
A61K39/00;A61K39/12;A61K39/29 |
主分类号 |
A61K39/00 |
| 代理机构 |
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