BENZAMIDINE DERIVATIVES FOR TREATMENT AND PREVENTION OF CANCER THERAPY INDUCED MUCOSITIS
摘要
Mucositis is the result of a complex process of interactive biologic phenomena that take place in both the epitelium and the submucosa, often leading to severe pain and increased risk of dangerous systemic infections. Mucositis is often a side effect during chemotherapy and radiation therapy. The benzamidine derivatives herein described are particularly effective for treating and preventing mucositis since they are acting simultaneously at the several phases that characterize this disease.
申请公布号
CA2600773(C)
申请公布日期
2013.06.11
申请号
CA20062600773
申请日期
2006.03.16
申请人
ROTTAPHARM S.P.A.
发明人
LETARI, ORNELLA;D'AMATO, MASSIMO MARIA;ZANZOLA, SIMONA;ARTUSI, ROBERTO;ROVATI, LUCIO CLAUDIO;CASELLI, GIANFRANCO;GIORDANI, ANTONIO