| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to a pyridine thio-derivative of general formula (I) or pharmaceutically acceptable salts thereof:, where Rand R, respectively, denote a hydrogen atom; Rand R, respectively, denote a hydrogen atom or a Calkyl group; X denotes -O- or -S-; Y denotes a Calkyl group, which can be substituted with a substitute selected from a group consisting of a hydroxyl group, Calkoxy group or -(R-O)-R(where Rdenotes a Calkylene group, Rdenotes a C-alkyl group which can be substituted with a halogen atom, and n denotes an integer from 1 to 2) and Z denotes a hydrogen atom. The invention also relates to pharmaceutical compositions based on said compounds, having antibacterial activity towards Helicobacter pyroli.EFFECT: obtaining novel compounds and a pharmaceutical composition based on said compounds, which can be used in medicine to prevent or treat diseases in which Helicobacter pylori participates, specifically gastritis, gastric ulcers, duodenal ulcers, gastric MALT lymphoma, hyperplastic gastric polyps or gastrointestinal malignant diseases.10 cl, 3 tbl, 14 ex |
