HETEROARENESULFONYL CINCHONA ALKALOID AMINE CATALYST AND MANUFACTURING METHOD FOR &bgr;-AMINOCARBONYL COMPOUND USING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a heteroarenesulfonyl cinchona alkaloid amine catalyst which solves the problems about the lowness of steric selectivity/reactivity of each product even if any of many asymmetric organic molecular catalysts used for the control of asymmetric space are used.

SOLUTION: The heteroarenesulfonyl cinchona alkaloid amine compound catalyst is obtained by introducing a hetroarylsulfonyl group onto the nitrogen atom of cinchona alkaloid to form an intramolecular hydrogen bond between the amide hydrogen of the sulfonamide and the hetero atom. A method for manufacturing a β-aminocarbonyl compound using the same is also provided.

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