发明名称 AGENT FOR ANTIPLATELET, ANTI-INFLAMMATORY AND CYTOPROTECTIVE THERAPY
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to medicine, and concerns an agent for prevention and treatment of cardiovascular diseases. The peptide 3-mercaptopropionyl-Phe-Ile-lle-Arg-Lys-Pro-Asp-Lys-NHis synthetised which has greater availability and lower price than known analogues; it possesses the antiplatelet, anti-inflammatory and cytoprotective properties.EFFECT: invention provides reduced spontaneous thrombocyte aggregation, inflammation inhibition by reducing histamine secretion, cell protection against neurotoxic actions of thrombin.1 cl, 4 ex
申请公布号 RU2483746(C1) 申请公布日期 2013.06.10
申请号 RU20120120386 申请日期 2012.05.17
申请人 FEDERAL'NOE GOSUDARSTVENNOE UNITARNOE PREDPRIJATIE "GOSUDARSTVENNYJ NAUCHNYJ TSENTR "NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT ORGANICHESKIKH POLUPRODUKTOV I KRASITELEJ" (FGUP "GNTS "NIOPIK") 发明人 RUMSH LEV DAVYDOVICH;STRUKOVA SVETLANA MIKHAJLOVNA;GORBACHEVA LJUBOV' RUFEHL'EVNA;BESPALOVA ZHANNA DMITRIEVNA;SIDOROVA MARIJA VLADIMIROVNA;FRID DMITRIJ ALEKSANDROVICH;FEL'DMAN BORIS MORDKOVICH;BURJACHKOVSKAJA LJUDMILA IVANOVNA
分类号 A61K38/00;A61K38/46;A61P29/00 主分类号 A61K38/00
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